Bacillus: Cellular and Molecular Biology
Horizon Scientific Press, 2007 - Science - 454 pages
Bacillus subtilis is one of the best understood prokaryotes in terms of molecular biology and cell biology. Its superb genetic amenability and relatively large size have provided powerful tools to investigate a bacterium in all possible aspects. Recent improvements in technology have provided novel and amazing insights into the dynamic structure of this single cell organism. The organism is a model for differentiation, gene/protein regulation, and cell cycle events in bacteria. This book presents an overview of the most recent exciting new research fields and provides a picture of the major cytological aspects of a model bacterium. The authors present the most recent knowledge on topics, such as the replication and segregation of the chromosome, cell division, replication and growth, the cell cycle, transcription, translation, regulation, the actin cyctoskeleton, the cell membrane and cell wall, biofilm formation, and sporulation. Also covered are DNA repair, the regulation of transcription through RNA molecules, and the regulation of protein activity through proteolysis. The authors seamlessly merge the fields of bacterial cell biology and molecular biology to provide an integral view of the bacterial cell, providing an understanding of the way a bacterial cell functions as a whole entity and in 3D, i.e. how it is spatially organized, and even how bacterial cells communicate with each other, or give their life for the sake of the whole community. This is an essential book for anyone interested in Bacillus, cell biology, bacterial genetics, and molecular biology.
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Acad acid actin actin-like activity antiterminator assembly Bacillus subtilis Bacillus subtilis.J bacterial Bacteriol binding Biol Carballido-López cell cycle cell division cell poles cell wall cell wall synthesis cellular chromosome segregation complex cytoplasmic cytoskeleton Dijl division proteins divisome DNA polymerase DNA replication DnaA DnaB domain elongation encodes enzymes Errington Escherichia coli eukaryotic filaments fluorescent forespore formation FtsA FtsZ function fusion gene expression genetic genome Gram-positive Graumann Grossman growth helical helicase homolog initiation interaction involved localization Losick mechanism membrane proteins Microbiol mother cell MreB MreBH MreC mRNA mutant Natl nucleoid operon pathways PBPs peptidase peptidoglycan polar primosome Proc promote protease proteolysis RecA regulation regulatory RNAs regulon repair replication fork replisome ribosomes ring RNAP role rRNA Scheffers septal septum sequence signal peptides specific Spo0A SpoIIIE Spore coat sporulation ssDNA strain structure subcellular substrate subtilis cells subunits termination tion Tjalsma transcription factor