Bacterial Endotoxins: Lipopolysaccharides from Genes to Therapy
Progress in Clinical and Biological Research, Volume 392 Bacterial Endotoxins Lipopolysaccharides From Genes to Therapy Proceedings of the Third Conference of the International Endotoxin Society, Held in Helsinki, Finland, August 15–18, 1994 Jack Levin, Carl R. Alving, Robert S. Munford, and Heinz Redl, Editors In the past two decades, the scope of research in the field of bacterial endotoxins has expanded dramatically. Bacterial Endotoxins: Lipopolysaccharides From Genes to Therapy contains the most recent basic and clinical work of researchers studying lipopolysaccharides (LPS), including everything from recent findings on the molecular genetics and biosynthesis of LPS, to various aspects of endotoxin tolerance. Assembling information from the work of renowned international researchers, the book is divided into ten well-organized sections, each of which includes papers representing the state of the art in LPS investigations. Specific topics covered in the text include:
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Increased Substitution of Phosphate Groups
Function of Lipopolysaccharide in the Invasion of Neisseria
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aeruginosa aminoguanidine anti-LPS antibiotic antigen assay bacteremia binding protein Biochem Brandtzaeg cell lines cellular cholerae clinical concentrations core culture cytokines detected dose effects EndoCAb endothelial cells endotoxemia endotoxic endotoxin Escherichia coli expression fatty acids Figure Galanos Genes to Therapy gingivalis Gram-negative human monocytes Immunol incubated induced Infect Immun inflammatory inhibition inhibitors iNOS interleukin Kupffer cells Legionella lethality levels lipid lipopolysaccharide lipopolysaccharide LPS LPS binding LPS-binding LPS-induced Mabs macrophages MAP kinase mediated membrane mice molecular molecules monoclonal antibody monocytes murine mutant neutrophil NF-kB ng/ml nitric oxide patients peptide pertussis phosphate phosphorylation plasma pmrA pneumophila polymyxin pretreatment production purified receptor release ReLPS response to LPS Rietschel role Salmonella SDZ MRL 953 sepsis septic shock serum shown signal soluble CD14 stimulation strain structure studies supernatants synthesis TNF-o TNFO Tobias treatment tyrosine tyrosine phosphorylation ug/ml Ulevitch RJ vitro vivo whole blood Wiley-Liss