Basic Principles and Practical Applications in Epidemiological Research

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World Scientific, 2002 - Medical - 367 pages
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Based on the concept of “conjecture and refutation” from the Popperian philosophy of science, i.e. looking for alternative causes, this book simplifies the design and inferences of human observational studies into two types: descriptive and causal. It clarifies how and why causal inference should be considered from the search for alternative explanations or causes, and descriptive inference from the sample at hand to the source population. Furthermore, it links the health policy and epidemiological concept with decisional questions, for which the basic measurement can be quality-adjusted survival time or quality-adjusted life year.
 

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Contents

Introduction to epidemiological research
1
Scientific hypothesis and degree of corroboration
39
Causal inference and decision
57
Basic principles of measurement
81
Basic measurements in epidemiological research
121
Study design
161
Adjustment and standardization of rates
197
Introduction to sampling method and practical
211
Followup study
233
Casecontrol study
259
How to critically review an empirical study
291
Application of epidemiological methods in health
307
References
341
Index
363
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