Basis for Cancer Management, Volume 784
L. Castagnetta, Italo Nenci, H. Leon Bradlow
New York Academy of Sciences, Jan 1, 1996 - Medical - 573 pages
This volume investigates the area of steroid actions in hormone-dependent cancer. Subjects covered: include molecular biology of steroid expression; oncogenes and tumour suppressor genes; steroid content and metabolism in breast tumours; regulation of cancer cell growth by hormones and anti-hormones; stromal-epithelial interactions in vitro; endocrine-related tumours (breast and prostate cancer); new specific enzyme inhibitors in the management of human cancer; mechanism of action of pure anti-hormones; selected oncogene products in cancer prognosis; clinical trials of breast and prostate cancer; and diet prevention and chemoprevention of main human tumours.
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Significance in Breast Cancer
Immunohistochemical Analysis of Steroid 5aReductase Type 1
Regulation and Inhibition of Steroid Sulfatase Activity in Breast Cancer
46 other sections not shown
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Acad activity analysis androgen antiestrogens apoptosis binding Biol biological breast cancer breast cancer cells cancer cell lines Cancer Res carcinoma cell cycle cell growth cell proliferation Chem Clin clinical concentrations correlation culture cysts cytosol DHEA differentiation effect endocrine Endocrinol enzyme epithelial cells epithelium estradiol estrogen receptor expression Figure function gene glucocorticoid receptor growth factor hormone receptors human breast cancer human prostate IGF-I immune increase incubated induced inhibition insulin receptor interaction levels LHRH ligand mammary tumor markers MCF-7 cells metabolism modulation molecular monoclonal antibody mRNA Natl neurons normal nuclear observed oncogene ovarian overexpression patients peptide phosphorylation primary Proc progesterone receptor prognostic prostate cancer protein pure antiestrogens regulation response role sequence serum sex hormone sex steroid smooth muscle specific staining Steroid Biochem steroid hormone stimulation stromal sulfatase tamoxifen therapy tissue transcription transfected treatment vitro vivo