Behavioral Models in Stress Research

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Nova Publishers, 2008 - Psychology - 226 pages
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Stress is an adaptive response that has developed throughout evolution, and is associated with multiple changes in the biochemistry, histology and physiology of an organism. As stress may induce or contribute to multiple neuropsychiatric disorders, the rigorous investigation of the neural substrates of stress has become a critical endeavour of contemporary biomedical science. This book explores the physiological responses that researchers have attempted to assess in stress-evoked behavioural changes, using both human and animal "experimental" models in clinical and non-clinical research. Though all aspects of the field have their challenges, animal experimental research of stress is a particularly difficult but meaningful task. This book provides succinct and relevant summaries of progress in the area of assessing stress response and the conditions contributing to it.
 

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Contents

Studying Behavior in Stress Research Not as Easy as One Would Think
1
Development and Validation of Alternative Animal Models of Anxiety and Depression Using Domestic Fowl
23
Animal Models of Anxiety Examining Their Validity Utility and Ethical Characteristics
55
The OpenField Model of Emotional Reactivity and Progress in the Molecular Genetics of Fear
73
Mouse Lines Selected for Difference in Sensitivity to bCCM also Differ in Spatial Memory Corticosterone Activation and Fear Reactivity
97
Optimization of the Chronic Stress Depression Model in C57 BL6 Mice Evidences for Improved Validity
111
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