Belmont Revisited: Ethical Principles for Research with Human Subjects

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Georgetown University Press, 2005 - Medical - 279 pages
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Research with human subjects has long been controversial because of the conflicts that often arise between promoting scientific knowledge and protecting the rights and welfare of subjects. Twenty-five years ago the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research addressed these conflicts. The result was the Belmont Report: Ethical Principles and Guidance for Research Involving Human Subjects, a report that identified foundational principles for ethical research with human subjects: respect for persons, beneficence, and justice.

Since the publication of Belmont, these three principles have greatly influenced discussions of research with human subjects. While they are often regarded as the single-most influential set of guidelines for biomedical research and practice in the United States (and other parts of the world), not everyone agrees that they provide adequate guidance. Belmont Revisited brings together a stellar group of scholars in bioethics to revisit the findings of that original report. Their responses constitute a broad overview of the development of the Belmont Report and the extent of its influence, especially on governmental commissions, as well as an assessment of its virtues and shortcomings.

Belmont Revisited looks back to reexamine the creation and influence of the Belmont Report, and also looks forward to the future of research--with a strong call to rethink how institutions and investigators can conduct research more ethically.

 

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Contents

On the Origins and Future of the Belmont Report
3
The Origins and Evolution of the Belmont Report
12
The Belmont Principles Influence and Application
27
The Dog in the NightTime Or The Curious Relationship of the Belmont Report and the Presidents Commission
29
Beyond Belmont Trust Openness and the Work of the Advisory Committee on Human Radiation Experiments
41
Relating to History The Influence of the National Commission and Its Belmont Report on the National Bioethics Advisory Commission
55
The Principles of the Belmont Report How Have Respect for Persons Beneficence and Justice Been Applied in Clinical Medicine?
77
The Belmont Principles Possibilities Limitations and Unresolved Questions
97
Justice beyond Belmont
136
Belmont Revisited through a Feminist Lens
148
Protecting Communities in Research From a New Principle to Rational Protections
165
Ranking Balancing or Simultaneity Resolving Conflicts among the Belmont Principles
184
Specifying Balancing and Interpreting Bioethical Principles
205
Max Weber Meets the Belmont Report Toward a Sociological Interpretation of Principlism
228
Looking Back to Look Forward
244
The Belmont Report
253

We Sure Are Older But Are We Wiser?
99
Toward a More Robust Autonomy Revising the Belmont Report Larry R Churchill
111
The National Commissions Ethical Principles With Special Attention to Beneficence
126
Contributors
266
Index
269
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About the author (2005)

James F. Childress is the John Allen Hollingsworth Professor of Ethics at the University of Virginia.

Eric M. Meslin is director of the Indiana University Center for Bioethics.

Harold T. Shapiro is president emeritus, Princeton University and a professor of economics and public affairs in the Woodrow Wilson School of Public and International Affairs.

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