Biocatalysis: Fundamentals and Applications

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John Wiley & Sons, Feb 27, 2007 - Science - 634 pages
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The whole range of biocatalysis, from a firm grounding in theoretical concepts to in-depth coverage of practical applications and future perspectives.
The book not only covers reactions, products and processes with and from biological catalysts, but also the process of designing and improving such biocatalysts.
One unique feature is that the fields of chemistry, biology and bioengineering receive equal attention, thus addressing practitioners and students from all three areas.
 

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Contents

1 Introduction to Biocatalysis
1
2 Characterization of a Biocatalyst
19
3 Isolation and Preparation of Microorganisms
43
4 Molecular Biology Tools for Biocatalysis
61
5 Enzyme Reaction Engineering
91
6 Applications of Enzymes as Bulk Actives Detergents Textiles Pulp and Paper Animal Feed
135
7 Application of Enzymes as Catalysts Basic Chemicals Fine Chemicals Food Crop Protection Bulk Pharmaceuticals
159
8 Biotechnological Processing Steps for Enzyme Manufacture
209
12 Biocatalysis in Nonconventional Media
339
13 Pharmaceutical Applications of Biocatalysis
373
14 Bioinformatics
413
15 Systems Biology for Biocatalysis
433
16 Evolution of Biocatalytic Function
457
17 Stability of Proteins
487
18 Artificial Enzymes
511
19 Design of Biocatalytic Processes
539

9 Methods for the Investigation of Proteins
243
10 Protein Engineering
281
11 Applications of Recombinant DNA Technology Directed Evolution
309
20 Comparison of Biological and Chemical Catalysts for Novel Processes
569
Index
593
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About the author (2007)

Andreas S. Bommarius obtained his diploma in Chemistry from the Technical Universtiy in Munich, Germany, and, in 1989, his PhD in Chemical Engineering from Massachusetts Institute of Technology (MIT) in Cambridge, MA,USA. In 1990, he joined Degussa as head of the Biocatalysis Laboratory and pilot plant. Since 2000 he is affiliated at Georgia Institute of Technology in Atlanta, Georgia, USA, as professor in the Schools of Chemical and Biomolecular Engineering and Chemistry and Biochemistry. His main research interests are novel redox enzyme systems, stability of protein biocatalysts, as well as novel catalysts through directed evolution.

Bettina R. Riebel obtained her diploma in Biology at the University of Cologne, Germany, and her PhD in Biochemistry at the University of D?sseldorf, Germany. She then occupied postdoctoral associate positions with Roche Diagnostics (then Boehringer Mannheim) in Penzberg and at the Research Center J?lich. As of 2000, she is part of the Institute of Pathology in the School of Medicine at Emory University in Atlanta, Georgia, USA, where her main research interests are in host-pathogen relationships, and specifically in tyrosine kinases and cell signaling.

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