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Transgenic mice as models for tau function axonopathy
Microtubulebinding of recombinant human tau4R and tau
LIST OF PUBLICATIONS
AD2 and PG5 aggregatie aggregation of tau Alzheimer Alzheimer's disease amyloid analysis antibody atomic force microscopy axonal belangrijke Biernat binding to MT biochemical brain cdk5 cellular conformational changes cyclin-dependent kinase Delacourte dementia demonstrated dimers electrophoretic epitopes expressed formation fosforylering fractions frontotemporal dementia FTDP-17 mutants Goedert hP-tau human protein tau human tau isolated from wild-type Leuven Leuven F MAb Tau-5 mammalian Mandelkow mds 1A Mds1 microtubule-associated protein microtubules molecular monomers MT-binding mutant tau mutant tau-P301 neurodegeneration neurofibrillary tangles neuronal observed orthologue overexpression paired helical filaments pan-tau patients PG5 epitopes pho&5A yeast pho÷5A phosphatases phospho-epitopes phosphorylated tau phosphorylation phosphorylation of tau physiological protein kinase protein tau-4R role SDS-PAGE Spittaels tau aggregation tau in yeast tau isoforms tau phosphorylation tau protein tau to MT tau-4R isolated tauopathy taxol-stabilized MT Terwel transgenic mice tubulin unbound Vandebroek vitro vivo western blotting wild-type tau-4R wild-type yeast strain yeast cells yeast kinases