Biochemical and Immuno-Histochemical Analysis of APP-Processing and Amyloid Pathology in Single and Multiple Transgenic Mice as Models for Alzheimer's Disease

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Leuven University Press, Sep 1, 2006 - Medical - 192 pages
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Contents

Rationale and aims
45
Structurefunction analysis of APP and its metabolites
65
BACE1 increases amyloid deposition in brain parenchyma
103
Neuronal or glial expression of human ApoB4 affects parenchymal
121
Mechanisms of PS1 and ApoE4 mediated amyloid pathology
143
Publications
161
Dankwoord
189
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