Biochemistry of nickel
In this timely monograph, the author summarizes the rapidly growing body of knowledge regarding nickel by providing a balanced discussion of its harmful and beneficial effects. Coverage includes a history of nickel; the chemistry of nickel, descriptions of the four known enzymes which contain nickel; and nickel metabolism in microbes, plants, and animals. Taken as a whole, Dr. Hausinger's work will highlight key features of this important element and help define future research.
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acetate acetogen acetyl coenzyme acid Acta aerogenes urease Alcaligenes eutrophus analysis animals autotrophic Bacteriol binding Biochem Biochemistry Biol Biophys Bradyrhizobium japonicum carbon monoxide dehydrogenase cells characterization Chem chemistry Clostridium thermoaceticum coenzyme A synthase coenzyme F430 coenzyme M reductase complex coordination cysteine demonstrated Desulfovibrio Diekert effects of nickel electron encoding enzyme Escherichia coli evidence function Furthermore growth Hausinger histidine hydrogen hydrogenase hydrogenase activity hyperaccumulators inhibitor interaction iron-sulfur jack bean urease levels ligands magnesium mechanisms membrane-bound metabolism metal ion metallocenter Methanobacterium Methanobacterium thermoautotrophicum methanogenesis Methanosarcina barkeri methyl coenzyme microbes microorganisms Moura mutants nickel carbonyl nickel center nickel compounds nickel concentrations nickel ion nickel resistance nickel transport nickel uptake nickel-containing nickel-dependent nickel(II nitrogen observed operon oxidation pathway peptide plants possess presence properties protein purified Ragsdale reaction redox reduced residues role sequence shown signal soluble species spectroscopic strain structure studies subunit synthesis Thauer tissues toxicity urea urease urease activity