Bioinformatics: Databases and Systems
Stanley I. Letovsky
Springer Science & Business Media, Aug 31, 1999 - Science - 304 pages
Bioinformatics brings computational methods to the analysis and processing of genomic data. Bioinformatics: Databases and Systems focuses on the issues of system building and data curation that dominate the day-to-day concerns of bioinformatics practitioners. Included are chapters by many of today's leading bioinformatics practitioners, describing most of the current paradigms of system building and curation, including both their strengths and weaknesses. Biological topics covered include sequence databases, metabolic pathways, phenotypes, variety collections, gene expression atlases and neuroinformatics. Species range from bacteria to mammals to plants. Software systems and technologies covered include OPM, CORBA, SRS, KLEISLI, ACEDB, Web-based integration and laboratory workflow.
Bioinformatics: Databases and Systems provides a valuable introduction for newcomers to the field, and a useful reference for veterans.
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Acedb allows analysis annotation application attributes bioinformatics BioKleisli biological Bioseqs bioWidgets browser chromosome clone complex components computational contains coordinates CORBA curation data model data sources databanks database management defined described developed display EcoCyc entries enzyme European Bioinformatics Institute example Figure files flat-files FlyBase format FROL GenBank gene expression gene products genetic Genome Database genomic sequence graphical HGMD homologous HOVERGEN implemented integrated interactions Java LabBase LabFlow laboratory MaizeDB Material metabolic reconstruction molecular biology Mouse Genome Multidatabase mutation NCBI neurons Nucleic Acids object object-oriented OPM Schema organisms orthologous parser pathways phenotype phylogenetic trees protein sequences Query Interface query language reactions records relational database relationships represent retrieval selected sequence identifiers server similar specific Step structure SWISS-PROT Sybase universal coordinate updated voxel widget workflow