Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins
John Wiley & Sons, Mar 24, 2004 - Computers - 504 pages
"In this book, Andy Baxevanis and Francis Ouellette . . . have undertaken the difficult task of organizing the knowledge in this field in a logical progression and presenting it in a digestible form. And they have done an excellent job. This fine text will make a major impact on biological research and, in turn, on progress in biomedicine. We are all in their debt."
—Eric Lander from the Foreword
Reviews from the First Edition
"...provides a broad overview of the basic tools for sequence analysis ... For biologists approaching this subject for the first time, it will be a very useful handbook to keep on the shelf after the first reading, close to the computer."
"...should be in the personal library of any biologist who uses the Internet for the analysis of DNA and protein sequence data."
"...a wonderful primer designed to navigate the novice through the intricacies of in scripto analysis ... The accomplished gene searcher will also find this book a useful addition to their library ... an excellent reference to the principles of bioinformatics."
This new edition of the highly successful Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins provides a sound foundation of basic concepts, with practical discussions and comparisons of both computational tools and databases relevant to biological research.
Equipping biologists with the modern tools necessary to solve practical problems in sequence data analysis, the Second Edition covers the broad spectrum of topics in bioinformatics, ranging from Internet concepts to predictive algorithms used on sequence, structure, and expression data. With chapters written by experts in the field, this up-to-date reference thoroughly covers vital concepts and is appropriate for both the novice and the experienced practitioner. Written in clear, simple language, the book is accessible to users without an advanced mathematical or computer science background. This new edition includes:
Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, Second Edition is essential reading for researchers, instructors, and students of all levels in molecular biology and bioinformatics, as well as for investigators involved in genomics, positional cloning, clinical research, and computational biology.
2 THE NCBI DATA MODEL
3 THE GENBANK SEQUENCE DATABASE
4 SUBMITTING DNA SEQUENCES TO THE DATABASES
5 STRUCTURE DATABASES
6 GENOMIC MAPPING AND MAPPING DATABASES
7 INFORMATION RETRIEVAL FROM BIOLOGICAL DATABASES
8 SEQUENCE ALIGNMENT AND DATABASE SEARCHING
11 PREDICTIVE METHODS USING PROTEIN SEQUENCES
12 EXPRESSED SEQUENCE TAGS ESTs
13 SEQUENCE ASSEMBLY AND FINISHING METHODS
14 PHYLOGENETIC ANALYSIS
15 COMPARATIVE GENOME ANALYSIS
16 LARGESCALE GENOME ANALYSIS
17 USING PERL TO FACILITATE BIOLOGICAL ANALYSIS