Bioinformatics and Functional Genomics
Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.
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accession number acid sequence algorithm amino acid amino acid identity analysis annotation approach archaea arrow bacteria Bioinformatics biological BLAST search cDNA cell cerevisiae Chapter chromosome clones ClustalW cluster codon coli compared complete genome database search deﬁned described DNA sequence domain encoding Entrez eukaryotic example exons FIGURE ﬁnd ﬁrst function GenBank gene expression genetic genome sequence genomic DNA homologous human disease human genome identiﬁed identify includes introns lipocalins matrix microarray microarray data molecular molecules motifs mouse mRNA multiple sequence alignment mutation NCBI nucleotide ofthe OMIM organisms ORNL orthologs output pairwise alignment Pfam phenotype phylogenetic tree predicted proﬁle prokaryotes protein families protein sequences protein structure protein-coding genes proteome PSI-BLAST quence RBP4 regions residues samples score selected sequence data server signiﬁcant species speciﬁc syndrome Table tein tion transcripts UniGene viral virus viruses yeast