Bioinformatics and Genomes: Current Perspectives
Miguel A. Andrade
Horizon Scientific, Jan 1, 2003 - Computers - 227 pages
A plethora of bioinformatics tools are available for exploiting the rapidly growing genomic, proteomic and structural data and the related databases. However, many researchers are unaware of these tools because they were published in a journal of narrow distribution or because they were described in technical language unfamiliar to the life scientist. In this book, leading bioinformaticists critically review the latest developments in their fields of expertise. Each chapter provides a clear explanation of the use, purpose and future potential of the tools for a given application. Topics include the use of multiple alignment methods, analysis of expression data, structural genomics, and protein structure prediction.
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Using Multiple Alignment Methods to Assess
Analysis of Expression Data
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algorithm Altschul amino acid analysis Andrade approach Apweiler automatically Bairoch BaliBase Bioinformatics Biol biological biosynthesis Bork cell classification clone ClustalW clustering coli comparison computational contains CORE index detected domain boundaries Eisenhaber Email entries enzymes etal eukaryotic example experimental Figure functional annotation gene expression Gene Ontology gene prediction Genet genome projects genome sequence genomic data Heringa homology human genome identified interactions linkers MeSH terms metabolic methods microarray molecular biology motif multiple alignment multiple sequence alignment Nucleic Acids Nucleic Acids Res ontology organisms ortholog pairs pathways patterns Pfam phylogenetic positions post-translational modifications problem processes profiles protein domain protein families protein folding protein function Protein Sci protein sequence protein structure proteome pseudogenes PSI-BLAST regions residues Sander score secondary structure segments sequence database sequence similarity signal simulation specific structural domains structural genomics superfamily SWISS-PROT T-Coffee target techniques thiamin YifB