Bioinformatics in the Post-genomic Era: Genome, Transcriptome, Proteome, and Information-based Medicine
During the past decade advanced computing technologies have revolutionized life sciences and medical research. Contains a comprehensive treatment of the role of bioinformatics in the emerging world of molecular medicine.
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Protein Structure Prediction
Introduction to Bioinformatics
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algorithms alignment amino acid analysis base basic binding bioinformatics BSML cDNA cell chromosomes clinical clusters coding regions codon complex contains context data sources designed discussion disease DNA sequence enzyme eukaryotic example experiments Figure folding fragments GenBank gene expression gene sequences gene-expression genetic grid hidden Markov model high-throughput human genome identify important individual information-based medicine infrastructure initiation interactions introns involves large number layer Markov models match messages metabolic methylated microarray microbead molecular biology molecules mRNA mutations NCBI neural networks nucleosome organisms output pathway pattern perceptron position predict problem programs protein sequence protein structure proteomic query reading frame records regulation regulatory represent residues result ribosome score secondary structure sequence data sequence database sequence information single solution specific splicing statistical Table tags techniques technologies template tertiary structure tion translation tRNA upstream vector weighting function