Biologic Effects of Light 1998
Michael F. Holick, Ernst G. Jung
Springer, Jul 31, 1999 - Medical - 512 pages
It is remarkable how much we take for granted the tremendous energy and vitality that the sun provides earth's inhabitants. As we enter the new millennium, it is worthwhile to review how our ancestors perceived the biologic effects of sunlight, and how science and medicine have advanced our knowledge about the biologic effects of light.
At the turn of the century, a multitude of investigators explored the use of sunlight and artificial radiation for treating a multitude of diseases. These explorations gave rise to photodynamic therapy, phototherapy, and chemophototherapy. However, enthusiasm for using sunlight and artificial radiation to treat disease was dampened with the birth of pharmacology.
It was the goal of the Fifth International Arnold Rikli Symposium on the Biologic Effects of Light, held in Basel, Switzerland, on November 1-3, 1998, to review the history of phototherapy and have some of the world's leading experts on the biologic effects of light provide new perspectives on the positive and negative effects of light. The general topics included a broad range of biologic effects of sunlight, artificial ultraviolet radiation and electromagnetic radiation. Special sessions on radiation and vitamin D and bone health, photoimmunology, biopositive effects of UV radiation, effects of electromagnetic currents and fields, and ocular and non-ocular regulation of circadian rhythms and melatonin, should be of particular interest to readers of Biologic Effects of Light.
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The Molecular Basis of Circadian Melatonin
Historical and New Perspectives
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AANAT activity aMT6s antigen atopic dermatitis Biol Biologic Effects blood pressure bone brain breast cancer bright light calcitriol calcium cellular chameleons circadian phase circadian rhythm clinical colon cancer concentration cortisol cultured cycle cytokine decrease depression dietary disease dose Effects of Light elderly entrained enzyme epidermal erythema exposed expression frequency gene high-dose UVA1 therapy Holick MF hormone human skin illumination increase induced keratinocytes Kripke lamps Langerhans cells light exposure light therapy light treatment magnetic field measured mechanism melatonin melatonin secretion metabolism mice modulation molecules ng/ml night observed pathway patients phase shift photoreceptors phototherapy pineal plasma previtamin D3 protein psoralen psoriasis rats receptor regulation response rickets risk samples seasonal affective disorder serum levels significant significantly sleep solar spectral subjects sunlight synthesis temperature therapeutic transcription tumors UV-B UVB irradiation UVB radiation vitamin D3 winter women