Biological Physics: Poincaré Seminar 2009
Bertrand Duplantier, Vincent Rivasseau
Springer Science & Business Media, Oct 4, 2010 - Mathematics - 170 pages
This new volume in the Poincaré Seminar Series, describing recent developments at the interface between physics and biology, is directed towards a broad audience of physicists, biologists, and mathematicians. Both the theoretical and experimental aspects are covered, and particular care is devoted to the pedagogical nature of the presentations. The first survey article, by Jean-Francois Joanny and Jacques Prost, describes the theoretical advances made in the study of "active gels", with applications to liquid crystals and cell motility. Jasper van der Gucht and Cécile Sykes then report on recent advances made with biomimetic model systems in the understanding of cytokinesis. The next article, by Jonathon Howard, presents several molecular models for motor proteins, which are compared with experimental results for kinesin. David Lacoste and Kirone Mallick then show theoretically that similar ratchet models of motor proteins naturally satisfy a fundamental time-reversal symmetry, the Gallavotti-Cohen fluctuation relation. Jean-Francois Allemand, David Bensimon and Vincent Croquette and their coauthors describe the latest advances made in the real-time single molecule study of the enzymes involved in DNA replication. Raymond E. Goldstein addresses the problem of understanding, from a physics perspective, the driving forces behind the biological evolution of multicellularity, using Volvocine algae as model organisms. Stanislas Dehaene finally addresses the major challenge of understanding the neuronal mechanism of consciousness, and speculates on the possible theoretical explanations of MRI experiments.
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A Physical Model of Cellular Symmetry Breaking
Motor Proteins as NanomachinesThe Roles of Thermal Fluctuationsin Generating Force and Motion
Fluctuation Relations for Molecular Motors
Studies of DNAReplication at the Single Molecule Level Using Magnetic Tweezers
Evolution of Biological Complexity
Conscious and Nonconscious Processes Distinct Forms of Evidence Accumulation?
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accumulation actin actin ﬁlaments active gel ATP hydrolysis attentional blink bead Biol Biophys bleb Cell Biology chemical coeﬃcient concentration conscious access contractile ring corresponds cortex cortical layer cytokinesis cytoskeleton deﬁned deﬁnition Dehaene depolymerization diﬀerent diﬀusion discrete DNA looping DNA molecule DNA replication dsDNA dynamics edge eﬀect energy enzymes equation equilibrium experimental extension ﬁeld Figure ﬁnd ﬁrst ﬂagella ﬂow ﬂuctuation relations ﬂuid force fork Gallavotti-Cohen Gucht hairpin helicase holoenzyme hydrodynamic increase instability kinesin lagging strand lamellipodium leading Lett magnetic tweezers masked measured mechanical membrane microtubule molecular motors motion motor domain Motor Proteins myosin Naccache nematic nonconscious observed oscillations Paluch parameter Phys polarization polymerase polymerization potential powerstroke presented primase primosome proﬁle Prost region replisome single molecule speciﬁc ssDNA stimulus stress subliminal priming subliminal processing substrate surface symmetry breaking synthesis task thermal ﬂuctuations threshold transition translocation unwinding velocity Volvox