Biological basis for risk assessment of dioxins and related compounds

Front Cover
Cold Spring Harbor Laboratory Press, 1991 - Medical - 501 pages
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Contents

Implications of the Reexamination of the Liver Sections from
13
Comparison of the Effects of PCDDs and PCDFs on Different
27
MECHANISM OF ACTION
54
The Male Reproductive System Is Highly Sensitive to In Utero
69
Effects of Dioxin Exposure in Humans at Seveso Italy
95
Panel Discussion Paolo Mocarelli Richard Kociba Joseph G Vos
111
Body Burden with PCDD and PCDF from Food Peter Furst
133
Dioxins and Related Chemicals in Humans and in
169
Possible Role in Species
321
Species Variation in Ah Receptor Transformation and
337
REGULATION OF GENE EXPRESSION
349
Mechanism of Action of TCDD as an Antiestrogen in Transformed
367
Development of a Molecular Basis for Dioxin Risk Assessment
379
Tumor Promotion by TCDD in Female Rats George Clark
389
Promotion of Hepatocarcinogenesis in Rats by PCDDs
405
IMPLICATIONS OF RECEPTORMEDIATED
415

HUMAN BODY BURDEN AND DISTRIBUTION IN TISSUE
215
Levels of TCDD in Selected Human Populations and Their
229
Discussion of Vietnam Veteran and Agent Orange Issues
259
Modeling of Human Exposure to TCDD and lTEQ in
277
RECEPTOR BIOCHEMISTRY
311
Receptorbased Approaches to Risk Assessment
441
Integration of MechanisticDosimetry Data into
459
Panel Discussion Robert J Scheuplein and William H Farland co
475
Epilogue Robert J Scheuplein Michael A Gallo and Kees
489
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