The Biological Monitoring of Exposure to Chemicals, Organic Compounds
Mat H. Ho, H. Kenneth Dillon
Wiley, Aug 14, 1987 - Medical - 352 pages
Provided here is an assessment of current applications and future directions for the biological monitoring of occupational exposure to chemicals (with the emphasis on organic chemicals). The book begins with an introduction and thorough review of the principles of biological monitoring, and reviews the investigations of scientists from all over the world dealing with specific applications in biological monitoring. Techniques that may provide great potential for the application of biological monitoring to the early detection or prevention of carcinogens are surveyed, and in addition, the book includes a discussion of the fluorescence method as a potential monitoring technique for early detection of occupational cancers.
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GENERAL PRINCIPLES FOR BIOLOGICAL MONITORING
IMPORTANT CONSIDERATIONS IN THE DEVELOPMENT
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1,1,1-trichloroethane 2-Methylpentane acid excretion acid in urine activity alveolar air alveolar concentration analysis analyzed Arch benzene biological monitoring biotransformation blood samples breath samples Brugnone cells charcoal tubes chemicals cholinesterase clinical coefficient compounds correlation creatinine cyclohexane detection determination effects Environ environmental enzyme erythrocyte esters ethanol expired air exposure concentration exposure to styrene exposure to toluene Figure gas chromatograph hippuric acid human hydrolysis indicators Industrial inhaled laboratory levels limit values liver m-xylene mandelic acid measured metabolism metabolites methanol method methylhippuric acid mg/L monitoring of exposure n-hexane o-cresol obtained occupational exposure organic oxidative parameters parathion Perbellini pesticides phenol phenylglyoxylic acid plasma porphyrins posure relative alveolar reported serum soluble solvents styrene styrene exposure subjects substance Table thioether tissue toluene toluene exposure toxic Toxicol trichloroethylene uptake urinary excretion urinary metabolites urine urine collected urine samples vapors venous blood ventilation workers exposed workshift xylene