What people are saying - Write a review
We haven't found any reviews in the usual places.
Reactive Metabolites as Key Intermediates in Pharmacologic
The Effect of Substrates and Inhibitors of Monoamine Oxidase
Dimethylnitrosamine Adducts Excreted in Rat Urine 11
72 other sections not shown
Other editions - View all
acetaminophen adducts animals aromatic hydrocarbons bay—region benzene benzo(a)pyrene benzphetamine Biochem Biol biological Biophys biphenyl bromobenzene butadiene carcinogenesis carcinogens cells cellular Chem chemical carcinogens complex compounds concentration conjugation Conney covalent binding cytochrome b5 cytochrome P-450 decreased dihydrodiols diol diol epoxides DMAP dose effect electrophilic enzymatic enzyme epoxide hydrolase Estabrook excretion formed fraction glucuronidation glutathione GSSG hamsters hepatic hepatic microsomal hepatocytes hydroxylation increase incubation induced inhibition inhibitor interaction isolated hepatocytes Jerina Jollow kidney lipid liver macromolecules mechanism membrane metabolic activation metabolites mg/kg mice microsomal Miller mixed-function molecular molecules monooxygenase mouse mutagenicity NADH NADPH necrosis Oesch Orrenius oxidase oxide oxygen pathway PCBs perfused peroxide Pharmacol phenobarbital phenol polycyclic pretreated quinone rabbit rat liver microsomes reaction reactive intermediates reactive metabolites reduced reductase role safrole shown species studies styrene substrates superoxide Table tion tissue toxicity transpeptidase urine vitro vivo y—glutamyl