Biology and Pathology of the Oocyte: Its Role in Fertility and Reproductive Medicine

Front Cover
Alan O. Trounson, Roger G. Gosden
Cambridge University Press, Jul 10, 2003 - Medical - 350 pages
The human oocyte or egg is the rarest and most rapidly ageing cell in the body, and yet one that is essential for fertility. This book is about the development and pathology of the oocyte, and new technologies to manipulate, enhance, and control fertility. World-leading experts have contributed to the first book for many years on basic and applied science of the egg, its clinical manipulation, and its pivotal role in reproductive medicine and biology. It will be an essential reference for scientists and clinicians in reproductive medicine and biology.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

The magic and mystery of the oocyte ex ovo omnia
3
Ontogeny of the mammalian ovary
13
The early stages of follicular growth
29
Modelling the dynamics of ovarian follicle utilization throughout life
44
Comparative aspects of oogenesis
53
Developmental biology
65
Oocytespecific gene expression roles in folliculogenesis fertilization and early development
67
Storage and functional recovery of molecules in oocytes
81
Morphology and pathology of the human oocyte
185
The legacy of mitochondrial DNA
209
Aneuploidy in ageing oocytes and after toxic insult
220
Genetic basis of primary ovarian failure
258
Technology and clinical medicine
271
Growth and development of the mammalian oocytegranulosa cell complex in culture
273
Human oocyte maturation in vitro
283
Follicular factors affecting oocyte maturation and developmental competenceTrounson2
305

Endocrine regulation of meiosis local and systemic hormonal influences
113
Checkpoint controls in mammalian oocytes
120
Fertilization fate of sperm components after ICSI
133
Activation of the mammalian egg
141
Clinical applications of symmetry asymmetry and polarity in early human development
163
Low temperature storage of follicular and ovulated oocytes
316
Fecundity of transplanted ovaries
327
Index
343
Copyright

Other editions - View all

Common terms and phrases

Bibliographic information