Biomacromolecules: Introduction to Structure, Function and Informatics

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John Wiley & Sons, Jan 16, 2007 - Science - 768 pages
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This book provides an integrated treatment of the structure and function of nucleic acids, proteins, and glycans, including thorough coverage of relevant computational biochemistry.

The text begins with an introduction to the biomacromolecules, followed by discussion of methods of isolation and purification, physiochemical and biochemical properties, and structural characteristics. The next section of the book deals with sequence analysis, analysis of conformation using spectroscopy, chemical synthesis, and computational approaches. The following chapters discuss biomolecular interactions, enzyme action, gene transmission, signal transduction, and biomacromolecular informatics. The author concludes with presenting the latest findings in genomics, proteomics, glycomics, and biomacromolecular evolution.

This text is an invaluable resource for research professionals wishing to move into genomics, proteomics, and glycomics research. It is also useful for students in biochemistry, molecular biology, bioengineering, biotechnology, and bioinformatics.

 

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Contents

CHAPTER 1 INTRODUCTION
1
CHAPTER 2 MONOMER CONSTITUENTS OF BIOMACROMOLECULES
15
CHAPTER 3 PURIFICATION AND CHARACTERIZATION
31
CHAPTER 4 BIOMACROMOLECULAR STRUCTURE NUCLEIC ACIDS
55
CHAPTER 5 BIOMACROMOLECULAR STRUCTURE PROTEINS
94
CHAPTER 6 BIOMACROMOLECULAR STRUCTURE POLYSACCHARIDES
147
CHAPTER 7 STUDIES OF BIOMACROMOLECULAR STRUCTURES SPECTROSCOPIC ANALYSIS OF CONFORMATION
183
CHAPTER 8 STUDIES OF BIOMACROMOLECULAR STRUCTURES CHEMICAL SYNTHESIS
220
CHAPTER 11 BIOMACROMOLECULAR CATALYSIS
322
CHAPTER 12 SIGNAL TRANSDUCTION AND BIODEGRADATION
398
CHAPTER 13 BIOSYNTHESIS AND GENETIC TRANSMISSION
436
CHAPTER 14 BIOMACROMOLECULAR INFORMATICS
515
CHAPTER 15 GENOMICS
558
CHAPTER 16 PROTEOMICS
594
CHAPTER 17 GLYCOMICS
655
CHAPTER 18 BIOMACROMOLECULAR EVOLUTION
680

CHAPTER 9 STUDIES OF BIOMACROMOLECULAR STRUCTURES COMPUTATION AND MODELING
249
CHAPTER 10 BIOMACROMOLECULAR INTERACTION
289

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About the author (2007)

C. STAN TSAI, PhD, served for more than twenty years as a professor of chemistry and biochemistry at Carleton University, Canada. He is the author of An Introduction to Computational Biochemistry, also from Wiley.

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