Biomarkers of Neurological and Psychiatric Disease

Front Cover
Paul C. Guest, Sabine Bahn
Academic Press, 2011 - Medical - 450 pages
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Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia.



  • Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research
  • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
  • All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
 

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Contents

Imaging brain microglial activation using positron emission tomography and translocator proteinspecific radioligands
19
The utility of gene expression in blood cells for diagnosing neuropsychiatric disorders
41
Proteomic technologies for biomarker studies in psychiatry Advances and Needs
65
Converging evidence of bloodbased biomarkers for schizophrenia An Update
95
Abnormalities in metabolism and hypothalamicpituitaryadrenal axis function in schizophrenia
145
Immune and neuroimmune alterations in mood disorders and schizophrenia
169
Behavioral and molecular biomarkers in translational animal models for neuropsychiatric disorders
203
Stem cell models for biomarker discovery in brain disease
239
Algorithm development for diagnostic biomarker assays
279
Challenges of introducing new biomarker products for neuropsychiatric disorders into the market
299
Toward personalized medicine in the neuropsychiatric field
329
Clinical utility of serum biomarkers for major psychiatric disorders
351
The future Biomarkers Biosensors Neuroinformatics and ENeuropsychiatry
375
Contents of Recent Volumes
413
Subject Index
451
Copyright

The application of multiplexed assay systems for molecular diagnostics
259

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