Biomaterials for Drug Delivery and Tissue Engineering:
Cambridge University Press, Sep 14, 2001 - Medical - 324 pages
Biomaterials and biological interfaces are expected to play a key role in promising areas of biotechnology (such as cardiovascular/neurological applications and drug, protein and gene delivery) for the future. Likewise, recent interest in dental/orthopedic applications is being driven by opportunities for improved biomaterial (mechanical) properties. This book focuses on biomaterials development from the perspective of materials design, coupled with tenets from cellular and molecular biology. Wide ranges of materials are investigated, spanning polymers, ceramics, metals, and hybrid materials. Chapters deal with orthopedic/dental biomaterials focus on designing functionalized polymeric, ceramic and composite scaffold; cardiovascular and neurologic biomaterials focus on improvement of hemocompatibility of biomaterials by surface modification strategies, cardiovascular drug delivery and tissue engineering and surface patterning techniques to enhance nerve regeneration and the development of novel biomaterials for stimuli-sensitive delivery, gene delivery and transdermal drug delivery. This volume represents important steps in strengthening the interface between materials science and bioengineering and should help catalyze collaborations that will result in significant new developments in the field of biomaterials.
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Formation of Three Dimensional Marrow Stromal CellPolymer
ChitosanCalcium Phosphate Scaffolds for Bone Tissue Engineering LL1 4
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2001 Materials Research acid adsorption alginate alloys alumina apatite behavior bioactive glass biocompatibility biodegradable Biomaterials Biomed blends bone buffer calcium cells chemical chitosan composite concentration copolymer crosslinking crystallinity crystallization culture degradation dendrimers density determined diffusion coefficient donor layer drug delivery elastic modulus electron encapsulation enhanced EXPERIMENTAL Figure films FITC-dextran fracture function gels GRGD hydrogel hydroxyapatite implantation increase incubation initial water content ISBN Materials Research Society matrix measured mechanical membrane microparticles microscopy Mikos molecular weight morphology MSCs N-surface nanoparticle nanophase osteoblast osteoblast adhesion p-NIPAm particles phosphate phosphate buffered saline plasma treatment PLGA polarity polyanhydride polybrene polymer polymeric pore porogen porosity porous powder protein ratio reaction receptor release retrovirus samples scaffolds shown sintered solubility solution specimens spinner flask substrate surface Symp synthesis terpineol testosterone tissue engineering UHMWPE vesicles virus adsorption vitro vitronectin vitronectin adsorbed vivo