Biomimetic Approaches for Biomaterials Development
Joao F. Mano
John Wiley & Sons, Feb 8, 2013 - Science - 606 pages
Biomimetics, in general terms, aims at understanding biological principles and applying them for the development of man-made tools and technologies. This approach is particularly important for the purposeful design of passive as well as functional biomaterials that mimic physicochemical, mechanical and biological properties of natural materials, making them suitable, for example, for biomedical devices or as scaffolds for tissue regeneration.
The book comprehensively covers biomimetic approaches to the development of biomaterials, including: an overview of naturally occurring or nature inspired biomaterials; an in-depth treatment of the surface aspects pivotal for the functionality; synthesis and self-assembly methods to prepare devices to be used in mineralized tissues such as bone and teeth; and preparation of biomaterials for the controlled/ sustained release of bioactive agents. The last part reviews the applications of bioinspired materials and principles of design in regenerative medicine such as in-situ grown bone or cartilage as well as the biomimetic techniques for soft tissue engineering.
The comprehensive scope of this book makes it a must-have addition to the bookshelf of everyone in the fields of Materials Science/Engineering, Nanotechnologies / Nanosciences, Medical Sciences, Biochemistry, Polymer Chemistry, and Biomedical Engineering.
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Surfaces Inducing Biomineralization
Biomimetic Nanostructured Apatitic Matrices
Nanostructures and Nanostructured Networks
Progress in DendrimerBased Nanocarriers
Tissue Analogs by the Assembly of Engineered
Biology Lessons for Engineering Surfaces
Fibronectin Fibrillogenesis at the CellMaterial
Nanoscale Control of Cell Behavior
Surfaces with Extreme Wettability Ranges
BioInspired Reversible Adhesives for Dry
Lessons from Sea Organisms to Produce
lnterfacial Forces and Interfaces in Hard
BioInspired 3D Environments for Cartilage
Soft Constructs for Skin Tissue Engineering
List of Abbreviations
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activity adsorbed adsorption affinity amino acid antibody apatite applications assembly behavior binding bioactive biocompatibility biological Biomacromolecules Biomater Biomaterials Biomed biomedical biomimetic Biotechnol bone calcium cell adhesion Cell Biol cellular Chem chemical coatings collagen complex components composition concentration conformation covalent cross-linking dendrimers density differentiation domains drug delivery elastin ELRs etal example fibers fibrillogenesis fibrils Figure FN molecules formation functional gene groups host hydrogels hydrogen bonding hydrophobic integrin interactions interface Langmuir layer ligand Macromolecules materials matrix mechanical properties mineral molecular recognition monomers nacre nanocomposites nanoparticles nanoscale nanostructured Natl natural organic peptide phosphate polymer polymerization polypeptide chain protein protein adsorption protein-engineered hydrogels receptors recombinant release scaffolds selectivity self-assembly sequence signaling Soft Matter solution specific spider silk strategies structure substrate superhydrophobic superhydrophobic surfaces synthetic target temperature template Tissue Eng tissue engineering vitro vivo wettability