Biophysical Modelling of Radiation Effects, Proceedings of the Workshop on Biophysical Modelling of Radiation Effects, Padua, Italy, 2-5 September 1991
Over the past 15 years, there has been progressive development of a series of biophysical models for the analysis and interpretation of the cellular effects of ionizing radiation. The theme of the workshop was the development of accurate models of the interaction of radiation with tissue and the origins of carcinogenesis - probably the most important issue in the field of radiation protection, since analyses of this kind are the only alternative to epidemiological studies. This volume concentrates on physical models and data analysis, and provides the reader with indications of critical benchmark experiments which need to be included in future research.
This book will be of interest to radiation biophysicists and biologists, medical physicists and anyone involved in radiological therapy and protection, as a valuable library addition reviewing all aspects of biophysical radiation effect modelling.
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Interpretation of the LET dependence of radiation induced lethal and
Analysis of the interaction of different radiations on the basis of DNA damage
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alpha particles analysis assumed assumption Barendsen Biol biological effect biophysical models calculated cancer carcinogenesis cell cycle cell lines cell nucleus cell survival cellular charged particles chromatin chromosome aberrations deletion delta rays dependence detector dicentric DNA DSB dose rate dose-rate double strand breaks electrons energy deposition equation experimental data experiments exposure extrapolation factor Figure fraction Goodhead D T heavy ion high dose high LET radiations human lymphocytes id id induced initial slope interaction inverse dose-rate effect ionisation ionizing radiation irradiation Katz kinetics lethal damage lethal events lethal lesions linear low doses low LET lymphocytes mammalian cells mean free path measured mechanisms molecular nanometre neutrons oncogenic parameters predictions probability produced protons radiation action Radiation Biology radiation protection radiation quality radiosensitivity repair risk Rossi sensitive single track specific suppressor gene survival curves target track structure tumour values Varma X-rays yield