Biopolymers at Interfaces, Second Edition

Front Cover
Martin Malmsten
CRC Press, Jan 15, 2003 - Science - 928 pages

This new edition features research from nearly 60 of the profession's most distinguished international authorities. Recognizing emerging developments in biopolymer systems research with fully updated and expanded chapters, the second edition discusses the biopolymer-based multilayer structures and their application in biosensors, the progress made in the understanding of protein behaviour at the air-water interface, experimental findings in ellipsometry and reflectometry, and recent developments concerning protein interfacial behaviour in microfabricated total analysis systems and microarrays. With over 3000 references, this is an essential reference for professionals and students in surface, pharmaceutical, colloid, polymer, and medicinal chemistry; chemical, formulation, and application engineering; and pharmacy.

 

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Contents

Macromolecular Adsorption A Brief Introduction
1
Driving Forces for Protein Adsorption at Solid Surfaces
21
Thermodynamics of Adsorption of Amino Acids Small Peptides and Nucleic Acid Components on Silica Adsorbents
45
Quantitative Modeling of Protein Adsorption
71
Interfacial Behavior of Protein Mutants and Variants
95
Orientation and Activity of Immobilized Antibodies
115
Interactions Between Surfaces Coated with Carbohydrates Glycolipids and Glycoproteins
165
Protein Adsorption Kinetics
199
Local and Global Optical Spectroscopic Probes of Adsorbed Proteins
435
Proteins on Surfaces Methodologies for Surface Preparation and Engineering Protein Function
467
Studies on the Conformation of Adsorbed Proteins with the Use of Nanoparticle Technology
497
Scanning Calorimetry in Probing the Structural Stability of Proteins at Interfaces
517
Ellipsometry and Reflectometry for Studying Protein Adsorption
539
Surface Plasmon Resonance Spectroscopies for Protein Binding Studies at Functionalized Surfaces
583
Neutron Reflection Study of Protein Adsorption at the SolidSolution Interface
609
XPS ToFSIMS and MALDIMS for Characterizing Adsorbed Protein Films
641

Mobility of Biomolecules at Interfaces
221
Protein Adsorption in Relation to Solution Association and Aggregation
259
Mechanism of Interfacial Exchange Phenomena for Proteins Adsorbed at SolidLiquid Interfaces
295
Interactions Between Proteins and Surfactants at Solid Interfaces
321
Toward Functionalized Polyelectrolyte Biofiltns
345
SelfAssembly of Functional Protein Multilayers From Planar Films to Microtemplate Encapsulation
367
Biological Activity of Adsorbed Proteins
393
Protein Interactions with Monolayers at the AirWater Interface
415
Interaction of Proteins with Polymeric Synthetic Membranes
671
Protein Adsorption in Intravenous Drug Delivery
711
Control of Protein Adsorption in SolidPhase Diagnostics and Therapeutics
741
Protein Interfacial Behavior in Microfabricated Analysis Systems and Microarrays
773
Protein Adsorption in the Oral Environment
811
Adsorbed Biopolymers Behavior in Food Applications
857
Index
901
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