Biopolymers at Interfaces

Front Cover
Martin Malmsten
CRC Press LLC, 1998 - Adsorption - 656 pages
Focusing on physiochemical aspects, this work provides an overview of biopolymer interfacial behaviour, advancing current understanding of the importance of protein adsorption in biophysical and biochemical processes, as well as the relevance of such phenomena in biomedicine. The text addresses fundamental aspects of biopolymer interfacial behaviour, such as adsorption kinetics, adsorbed layer structure and dynamics, interfacial orientation, effects of self-assembly on protein adsorption, interactions between biopolymer layers, and interfacial exchange.

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Contents

Driving Forces for Protein Adsorption at Solid Surfaces
27
Thermodynamics of Adsorption of Amino Acids Small Peptides
55
Quantitative Modeling of Protein Adsorption
89
Interfacial Behavior of Protein Mutants and Variants
119
Methodologies for Surface Preparation
143
Local and Global Optical Spectroscopic Probes of Adsorbed
181
Orientation and Activity of Immobilized Antibodies
221
Glycolipids and Glycoproteins
281
Mechanism of Interfacial Exchange Phenomena for Proteins
453
Interactions Between Proteins and Surfactants at Solid
485
Introduction
514
Direct Measurements of Interactions Between Proteins
534
Chemical Approaches to Minimizing Protein Fouling
543
Interaction of Proteins with Polymeric Synthetic Membranes 513
551
Protein Adsorption in Intravenous Drug Delivery
561
Control of Protein Adsorption in SolidPhase Diagnostics
597

Kinetics of Protein Adsorption
321
Mobility of Biomolecules at Interfaces
363
Protein Adsorption in Relation to Solution Association
409
Studies on the Conformation of Adsorbed Proteins with the Use
627
Index
651
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