Bioradicals Detected by Esr Spectroscopy

Front Cover
Springer Science & Business Media, Nov 29, 1995 - Science - 337 pages
0 Reviews
This book is based on two keywords: Bioradical and ESR. Bioradical is a newly coined word which encompasses paramagnetic species in biological systems, such as active oxygen radicals and transition metal ions. Research on the structure and function of bioradicals has been attrac ting growing attention in the field of biological science, and comprehensive investigations from many fields are helping to understand the real features of these species. ESR spectroscopy also has interdisciplinary features in that its techniques have been applied to many fields, ranging from physics to medicine. It was our hope, therefore, that this book would help to clarify many aspects of bioradicals and that significant progress would be achieved in combining basic research from many different fields. This book arises from the First International Conference on Bioradicals Detected by ESR Spectroscopy (ICBES), which was held in Yamagata, a city in the Yamagata Prefecture of Japan, in 1994. About 300 participants from 16 different countries attended this conference, and about 170 papers were presented. This book is a collection of contributions from the conference and also contains eleven chapters selected by the editorial board, based on sugges tions from the members of the international editorial board of ICBES. The Yamagata Technopolis Foundation is developing a biomedical technology for the 21st century based on life science fused with material and physical science. Based on such a techno logy, the Foundation plans to share its fruits all over the world.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Overview of bioradicals and ESR technology
1
Chemistry of oxygen radicals
17
Physics technology and applications to bioradicals
31
Scanning tunneling microscopy STM methods for detecting ESR of a single spin center
49
An open space ESR spectrometer and its application to high dielectric loss samples
63
New experimental modalities of low frequency electron paramagnetic resonance imaging
69
Whole body electron spin resonance imaging spectrometer
93
Development of the rapid field scan Lband ESRCT system
103
Recent developments in spin labeling
173
Electron spin resonance imaging of rat brain
193
ESEEM spectroscopy probing active site structures of metalloproteins
203
Nitric oxide a versatile biological ligand for hemeproteins
217
Vitamin E and antioxidant interactions in biological systems
237
Antioxidant activity of vitamin E and vitamin C derivatives in membrane mimetic systems
259
Action of antioxidants as studied by electron spin resonance
277
In vivo EPR spectroscopy
285

Spin trapping
113
History of spin trapping in Japan
143
In vivo ESR observation of bioradical metabolites in living animals
155
Dithiocarbamate spin traps for in vivo detection of nitric oxide production in mice
163
Pharmaceutical aspects of ESR investigations on drug delivery systems tissues and living systems
301
In vivo ESR measurement of free radical reactions in living animals using nitroxyl probes
321
Subject index
335
Copyright

Other editions - View all

Common terms and phrases

About the author (1995)

Packer is regarded as the world's foremost antioxidant research scientist. Head of the Packer Lab at the University of California at Berkeley. He is the senior scientist at the prestigious Lawrence Berkeley Laboratory.

Bibliographic information