Biotechnology: Science, Engineering, and Ethical Challenges for the Twenty-First Century

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Frederick B. Rudolph, Larry V. McIntire
Joseph Henry Press, Mar 22, 1996 - Science - 296 pages
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Biotechnology-the manipulation of the basic building blocks of life-is rapidly advancing in laboratories around the world. It has become routine to refer to DNA fingerprints and genetically engineered foods.
Yet the "how to" of biotechnology is only the beginning. For every report of new therapies or better ways to produce food, there is a Jurassic Park scenario to remind us of the potential pitfalls.
Biotechnology raises serious issues for scientists and nonscientists alike: Who will decide what is safe? Who will have access to our personal genetic information? What are the risks when advanced science becomes big business?
In Biotechnology, experts from science, law, industry, and government explore a cross-section of emerging issues. This book offers straightforward explanations of basic science and provides insight into the serious social questions raised by these findings.
The discussions explore five key areas:

  • The state of the art in biotechnology-including an overview of the genetic revolution, the development of recombinant DNA technology, and the possibilities for applying the new techniques.
  • Potential benefits to medicine and the environment-including gene therapy, the emerging area of tissue engineering and biomaterials, and the development of therapeutic proteins.
  • Issues in technology transfer-focusing on the sometimes controversial relationship between university research centers and industry.
  • Ethics, behavior, and values-exploring the ethical issues that surround basic research and applications of new technology, with a discussion of scientific misconduct and a penetrating look at the social impact of genetic discoveries.
  • Government's role-including a comparison of U.S., European, and Japanese policies on pharmaceutical and biotechnology development.

Biotechnology is here to stay, and this volume adds immeasurably to understanding its multiple aspects and far-reaching implications. This book will be of interest to scientists and industry leaders involved in biotechnology issues-and it will be welcomed by the concerned lay reader.
Frederick B. Rudolph, Ph.D., is a professor of biochemistry and cell biology at Rice University and is executive director of the Institute of Biosciences and Bioengineering.
Larry V. McIntire, Ph.D., is the E. D. Butcher Professor of Chemical and Biomedical Engineering at Rice University and is chair of the Institute of Biosciences and Bioengineering.

 

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Contents

THE FOUNDATION OF BIOTECH 1
Advances in Cell and Molecular Biology 15
Structural Biology as It Applies to Biotechnology 28
The Future of Biotechnology 43
BIOTECHNOLOGY APPLICATIONS TODAY AND 61
Beyond Genetic Diseases 72
The Union of Biology and Engineering 88
An Engineering Per 100
National Science Foundations Perspective on University Industry Interaction 147
Conflict of Interest in Basic Biomedical Research José E Trías 152
ETHICS BEHAVIOR AND VALUES IN SCIENCE AND SOCIETY 173
Regulating and Investigating Scientific Research Barbara Mishkin 183
Ethical Decision Making in a Pluralistic Society Daniel E Koshland Jr 191 17 Ethical Issues Surrounding the New Technology as Applied to Health C...
Biotechnology Applications and Womens Health Issues Ruth Ellen Bulger 208
Comparison of U S European and Japanese Policies Affect ing Pharmaceutical and Biotechnology Development 225
The Making of Environmental Policy Decisions 246

A Promising Technology Gene F Parkin 113
THE CHALLENGES OF TECHNOLOGY TRANSFER 129

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