Bipolar Affective Disorders: Etiology and Treatment
Jörg Walden, Dr. Heinz Grunze
Georg Thieme Verlag, 2004 - Medical - 92 pages
Bipolar disorder has increasingly become a main focus of interest in psychiatry. This is reflected by the obvious success of the 1st edition of this book by Walden and Grunze. Due to both the scientific and therapeutic progress it appears now necessary to have this revised version of the book. Concerning therapeutic concepts major progress has been made with the introduction of new antiepileptic drugs such as lamotrigine and atypical antipsychotics to the treatment portfolio of bipolar disorder. But also the scientific evaluation of psychotherapies as cognitive behavioural therapy and psychoeducation constitutes a substantial progress. It becomes clear that modern treatment concepts should integrate both pharmacological and non-pharmacological treatment modalities.
However, despite the rapid increase of knowledge this book is still designed to be a quick reference on the causes and treatment of bipolar disorder, and I hope that it will be a useful tool for the daily clinical practice.
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Epidemiology and Social Consequences
Classification and Course
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according to DSM activity acute mania acute treatment antiepileptic antiepileptic agents antimanic efficacy atypical antipsychotic atypical antipsychotic agents benzodiazepines bipolar affective disorder bipolar depression bipolar disorder bipolar patients calcium antagonist carbamazepine clinical clozapine co-morbidity Combination therapy controlled studies course Cyclothymia depressive episodes depressive phase diagnosis diseases Dosages dose double-blind duration dysphoric mania efficacy demonstrated electroconvulsive therapy elevated especially etal euphoric mania exhibit frequent gabapentin genes genetic Grunze hypomania hypomanic hypomanic episode illness increase intracellular calcium lamotrigine lithium level lithium therapy long-term manic episode medication metabolism mg/day mild mixed episode monotherapy mood stabilizers nimodipine occur olanzapine open studies oxcarbazepine patients with bipolar placebo plasma level possible prophylactic prophylaxis protein Psychiat Psychiatry quetiapine rapid cycling patients receptor recurrence relapse risk risperidone serum level side effects sleep sub-syndromal substances switch Table therapeutic tients tolerated Treatment algorithm treatment of acute treatment of bipolar unipolar valproate weeks ziprasidone