Bone Disease of Organ Transplantation
Juliet Compston, Elizabeth Shane
Academic Press, Jan 26, 2005 - Medical - 350 pages
Bone disease, particularly osteoporosis, has emerged as a common and serious complication of solid organ transplantation. In recent years there have been real advances in our understanding of the pathogenesis and pathophysiology of bone loss, however treatment studies have been relatively sparse and successful strategies to reduce skeletal morbidity after transplantation remain to be clearly established. This book provides a unique resource for the many health professionals involved with transplantation of bone disease, both in terms of its scientific background and the management of the disease in clinical practice.
-Basic Transplantation and Bone Biology
-Pathogenesis of Transplantation Related Bone Disease
-Clinical Features of Transplantation Bone Disease
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activity alendronate allograft associated biopsies bisphosphonates bone density bone disease bone formation bone loss bone marrow bone mass Bone Miner Res bone mineral density bone resorption bone turnover calcineurin inhibitors calcitonin calcitriol calcium cardiac transplantation cells chronic Clin Endocrinol Metab clinical cyclosporine cystic fibrosis cytokines decreased doses effects on bone end-stage Endocrinology Epstein estrogen etidronate femoral neck fracture rates fracture risk glucocorticoid-induced glucocorticoids graft heart transplant histomorphometric hyperparathyroidism hypogonadism immunosuppressive incidence increased bone inhibits kidney transplantation liver disease liver transplantation long-term low bone lumbar spine lung transplantation months after transplantation necrosis normal organ transplantation osteoblasts osteocalcin osteonecrosis osteopenia Osteoporos Int osteoporosis pamidronate parathyroid hormone Pediatr post-transplant post-transplantation postmenopausal prevalence prevention randomized receptor reduced regimens renal osteodystrophy renal transplantation risk factors role serum Shane skeletal T-cell T-score tacrolimus testosterone therapy transplant patients transplant recipients treatment vertebral fractures vitamin vitamin D women