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Cellular Work in the Brain
Circulation and Oxygen Consumption in the Brain
Utilization of Substrates by Brain Tissues
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a-KG acidosis Acta activity amino acids ammonia anaesthesia anaesthetics animals arterial aspartate B. K. Siesjo barbiturates Biochem catalysed CBF and CMRQj cell cerebral blood flow cerebral cortex cerebral metabolism changes Chapter citric acid cycle CO2 tension complete ischemia cortical cytoplasmic decrease dehydrogenase discussed effect energy metabolism enzyme equilibrium Figure flux Folbergrova function GABA glial glucose concentration glucose consumption glucose transport glutamate glutamine glycogen glycolysis glycolytic halothane hypercapnia hypoglycemia hypothermia hypoxia imole increase in CBF indicate induced intracellular ischemia ketone bodies lactate lactate concentration measurements membrane metabolic rate metabolites method Michenfelder mitochondria mitochondrial molecules NADH Neurochem neurons Nilsson normal nucleotides occurs oxygen oxygen consumption pathway PCQj perfusion phenobarbital phosphate phosphorylation Physiol pyruvate rat brain ratio reaction redox reduced Reproduced with permission respiratory results obtained seizures studies substrate synthesis technique temperature tion tissue concentrations uptake values venous vitro vivo