Breast Cancer: Cellular and Molecular Biology

Front Cover
Marc E. Lippman, Robert B. Dickson
Springer Science & Business Media, Aug 31, 1988 - Medical - 398 pages
Where do you begin to look for a recent, authoritative article on the diagnosis or management of particular malignancy? The few general oncology text books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre quently publish good in-depth reviews of cancer topics, and published sym posium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by divid ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
 

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Contents

Heterogeneity of Genetic Alterations in Primary Human Breast
25
Different Mechanisms are Responsible for Oncogene
49
Identification of Oncogenes in Breast Tumors and their Effects
67
Epidermal Growth Factor Receptors in Human Breast Cancer
93
Control of Human Breast Cancer by Estrogen Growth Factors
119
Structure and Function of the PS2 Gene and Estrogen Receptor
185
Structure Regulation
207
Biochemical Mechanisms
223
Regulation of Development of the Normal Mammary Gland
251
MMTV as a Model for Gene Expression in Mammary Tissue
267
The Activation of Cellular Oncogenes by Proviral Insertion
283
Steroid Hormone Regulation of Cultured Breast Cancer Cells
307
The Role of Epidermal Growth Factor in Normal
343
Tumorassociated Growth Factors in Malignant Rodent
363
Index
391
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