Breast Cancer Treatment by Focused Microwave Thermotherapy
The only book of its kind - inventor, Dr. Alan J. Fenn, provides exclusive information on the revolutionary, non-invasive breast cancer treatment of wide-field focused microwave thermotherapy! Breast Cancer Treatment by Focused Microwave Thermotherapy provides a comprehensive overview of the technology and application of a unique, wide-field focused microwave thermotherapy (heat treatment) technology, based on adaptive phased array systems, used in clinical trials for the treatment of small and large breast cancer tumors. Breast cancer cells generally have high-water content and high-ion content as compared to the surrounding normal breast tissues, and they are preferentially heated and killed with microwave energy, particularly with focused microwave energy. This preoperative focused microwave thermotherapy technology is being explored in combination with standard breast conservation techniques to increase tumor cell kill, shrink tumors, improve surgical margins, increase the use of breast conservation, and reduce tumor recurrence. Based on the author and other researchers experiences and observations over the last 16 years, this book offers information on both previously published, peer-reviewed journal articles and important, never before published information to provide a complete review of the clinical rationale, theory, technology, methods, and preclinical and clinical results for breast cancer treatment by ultrasound-guided, wide-field focused microwave phased array thermotherapy for medical students, surgical, medical and radiation oncologists, pathologists, medical physicists, biomedical engineers, and other specialists and breast cancer researchers. No other book has attempted to capture all of this information in one volume!
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Focused Microwave Radiation Theory
Preclinical Results for Focused Microwave
CLINICAL RESULTS FOR PREOPERATIVE
Phase II Thermal Dose Escalation Study
Randomized Study of Preoperative Focused
adaptive phased array Ann Surg Oncol anthracycline benign breast breast cancer breast cancer tumors breast carcinomas breast compression breast conservation breast cyst breast lesions breast thermotherapy breast tumor breast-conserving surgery cancer cells catheter Clin Oncol cyclophosphamide cysts dB/cm DCIS dielectric constant docetaxel doxorubicin E-field epirubicin equivalent minutes excision Fenn fibroadenomas focused microwave phased focused microwave thermotherapy Gardner RA glandular Hyperthermia Int J Hyperthermia intact breast invasive breast cancer ionic conductivity lumpectomy mastectomy measured microwave applicators microwave energy microwave field microwave phased array microwave power motherapy necrosis neoadjuvant node normal breast tissue NSABP paclitaxel patients phased array thermotherapy positive margins preoperative chemotherapy preoperative focused microwave primary breast radiation therapy recurrence sensor skin specific absorption rate surgery-alone arm tamoxifen temperature probe ther thermal dose thermochemotherapy thermotherapy arm thermotherapy system thermotherapy treatment treat tumor cell kill tumor necrosis tumor response ultrasound water content waveguide waveguide applicators
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