Breast Conservation Versus Mastectomy: Patient Survival in Day-to-day Medical Practice and in Randomized Studies : Report to the Chairman, Subcommittee on Human Resources and Intergovernmental Relations, Committee on Government Operations, House of Representatives
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1.5 percentage points 4-cm limit 5-year survival rate actuarial estimate adjusted Breast Cancer breast cancer patients Breast conservation Mastectomy breast-conservation and mastectomy breast-conservation patients calculated combined-treatments survival rate confidence interval criteria Cross design comparison Danish day-to-day medical practice difference in survival effective n's effectiveness of breast-conservation English studies EORTC following breast-conservation therapy included kinds of patients lumpectomy mastectomy patients mastectomy survival rates medical practice data meta-analysis Milan multicenter randomized studies multicenter studies National Cancer Institute nodal dissection node-negative patients node-positive odds of surviving odds ratio patient characteristics patients who received point of equivalence potential differences propensity scores propensity-score Quadrantectomy radiation rate for breast-conservation rate for mastectomy received breast-conservation therapy received mastectomy rounded SEER analysis SEER patients selected SEER similar single-center and multicenter six randomized studies standard error statistically significant survival following breast-conservation Technical Appendix therapy and mastectomy treatment groups tumor-size limit tumors larger Umberto Veronesi Veronesi