Bull's-eye: Unraveling the Medical Mystery of Lyme Disease

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Yale University Press, 2004 - Health & Fitness - 285 pages
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In this riveting account of medical sleuthing, Dr. Jonathan A. Edlow tells the history of the discovery of Lyme disease over centuries and continents. He also provides the latest information about the disease and its treatment, explaining the recent widespread outbreaks and examining the controversies that have swirled over the diagnosis, vaccine, treatment, and even definition of Lyme disease. In a new preface, Dr. Edlow updates recent developments and controversies in Lyme disease research, discusses reactions from the two "camps" of the Lyme disease community, and writes about some of the reactions of patients to the book.
"A valuable guide for dealing with emerging diseases. . . . The best thing of all about Bull's-Eye is that it lays out the unknowns along with the knowns, the mainstream view along with alternative readings, and thus reveals science for what it is: a perpetual, and admirable, work in progress."--Andrew C. Revkin, New York Times Book Review
"Bull's-eye is a compelling mystery and a riveting account of science in action."--Robert B. Parker
"The story of an emerging infection and its history. . . . Beautifully written. . . . Anyone who is curious about Lyme disease or medical discovery in general will find this book interesting reading."--Raymond Dattwyler, New England Journal of Medicine

 

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Bull's-eye: unraveling the medical mystery of Lyme disease

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Most lay readers will here find more than they ever wished to know about the classification of American and European ticks and the details of a complicated and lengthy scientific investigation ... Read full review

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Contents

A Family Under Siege
1
A Little Girls Knee
9
The Broad Street Pump
17
An Appointment in New Haven
28
An Outbreak of Arthritis
36
An Outbreak of Dermatitis
46
The European Connection
55
Further Work in Europe
62
The Diagnosticians Dilemma
160
Ambiguity in the Lab
170
A Tick with Two Toxins
179
Cracks in the Theory
188
Another Paradigm
199
Therapeutic Adventures
212
Genomes and Vaccines
221
Legal and Political Battles
231

The Blind Men and the Elephant
72
The Connection with Ticks
81
An Intersection of lnvestigations
90
From the Alps to the Rockies
102
To Treat or Not to Treat?
110
The Scramble for the Cause
118
The Culmination of Efforts
130
Progress to the End of the 1980s
141
A Geographical Expansion
150
An Independent Reality
243
Epilogue
251
Symptoms of Lyme Disease
255
TickBorne Disease in Human and Animals
256
Sources
259
Glossary
275
Index
279
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