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History and Economics Sidney D Nelson
Guidelines for Drug and Analog De 10 The Quantitative Analysis
Drug Absorption Distribution
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A. H. Conney absorption Academic Press acetaminophen acetylation Acta activity agents agonists aliphatic amines amino acids amphetamine analogs antibodies aqueous Arch arene oxides aromatic atom B. B. Brodie benzo(a)pyrene beta sheet Biochem Biol biological Biophys blood flow Cancer carbon carcinogenic cells Chem chemical Clin complex compounds concentration conjugation covalent cytochrome P-450 decrease drug metabolism effects enzyme epoxide equation example excretion formation gastric glucuronidation glutathione hapten hepatic hexobarbital hydrogen bonds hydrophobic hydroxylation increase inducers inhibition inhibitors interactions intermediate intestine isoniazid J. A. Miller J. R. Gillette liver macol mechanism membrane Metab metabolite microsomal moiety molecular molecules N-oxidation oxidase pathway penicillin Phar Pharm Pharmacol Pharmacology Physiol plasma polar Proc protein R. L. Smith rats reactions reactive receptor reductase species structure studies substituent substrate synthesis Ther tion tissue tive toxicity transferase undergo vitro vivo Xenobiotica xenobiotics York