Cholinergic Function and Dysfunction
A. Claudio Cuello
Elsevier, 1993 - Medical - 462 pages
Presents a comprehensive update of central cholinergic mechanisms from their most molecular aspects to possible clinical applications modifying cholinergic neurotransmission. A considerable number of high-calibre scientists from several continents contributed to this volume.
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Organization of CNS Cholinergic Systems
CNS Cholinergic Receptors
The Neurobiology of Acetylcholinesterase
Synthesis Storage and Release of Acetylcholine
Turnover of Acetylcholine and Control of its Release
Molecular Aspects of Acetylcholine Release
Trophic Influences on CNS Cholinergic Neurons
ElectroPhysiological Aspects of Central Cholinergic Mechanisms
acetyl acetylcholine receptor acetylcholinesterase ACh release acid afferents afﬁnity Alzheimer's disease antagonist axons basal forebrain BDNF binding Biochem Biol Brain Res brainstem Ca2+ calcium carbachol cDNA central cholinergic cerebral cortex ChAT activity choline acetyltransferase cholinergic neurons cholinergic system cholinesterase clinical cloned cortical Cuello deﬁcits depolarization drugs effects Elsevier enzyme excitatory expression ﬁbers ﬁeld ﬁring ﬁrst function gene hippocampus identiﬁed increase inﬂuence inhibition inhibitory injection innervation input lesions lithium M2 receptors mechanisms mediated membrane modulation molecular mRNA muscarinic acetylcholine receptor muscarinic agonists muscarinic receptor muscarinic receptor subtypes Natl nerve growth factor nerve terminals nervous system Neurochem Neurosci neurotransmitter neurotrophic nicotinic receptors nucleus basalis PGO waves Pharmacol pharmacological Physiol pirenzepine postsynaptic potential presynaptic protein rat brain regions REM sleep response reticular role selective sequence signiﬁcant speciﬁc Steriade stimulation studies subunits synaptic vesicles synaptosomes synthesis tegmental thalamic tion tissue Torpedo transmitter vesamicol vitro vivo