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Aims of the present study
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Acta Physiol Scand action potential adenylate cyclase adenylate cyclase activity atrial contractility binding bradykinin C-fibre C-fibre afferents Calcitonin gene calcitonin gene-related peptide capsaicin-sensitive cardiac contractility cardiac sensory nerves cells CGRP tachyphylaxis chronotropic chronotropic effects Coleridge contractile force coronary arteries coronary vascular tone effects of capsaicin effects of CGRP endothelium European J Pharmacol FISCHER FRANCO-CERECEDA guinea-pig guinea-pig and rat guinea-pig heart HOKFELT human CGRP immunoreactivity increased overflow incubated induced influence inhibition inotropic inotropic effects ischaemia isolated Lembeck LUNDBERG Malliani metoprolol myocardial nerve fibres neurokinin neuropeptide nicotine NKA-LI NPY-LI ouabain outflow of CGRP-LI overflow of CGRP-LI perfusion peripheral positive inotropic precontracted prostaglandin rat CGRP rat heart reflex relaxation release of CGRP release of CGRP-LI reserpine right atrium SARIA sensory nerves sensory neurons SP-IR SP-LI spinal cord stimulatory effects substance systemic capsaicin pretreatment tachykinins tachyphylaxis Thoren tissue Uchida & Murao unmyelinated vagal afferents vasodilatation vasodilator ventricles ventricular