Calcium Signalling in the Nervous System

Front Cover
Wiley, 1995 - Medical - 206 pages
Calcium ions play an important role in the function of excitable cells, from the triggering of impulses in nerve cells to the regulation of biochemical pathways and basic cellular functions of all cell types in the nervous system. Calcium signalling is the main coupling mechanism linking external stimuli, via the membrane, with intracellular processes. Calcium Signalling in the Nervous System provides an up-to-date account of the most fundamental aspects of calcium signal generation in the nervous system, including pathways for Ca2+ influx, buffering in the cytosol, involvement of intracellular calcium stores and Ca2+ extrusion. The book also gives an overview of the most important aspects of interaction of Ca2+ ions with other messenger systems, the functional meaning of Ca2+ ions, as well as the pharmaceutical tools used for their dissection and modulation. The role of calcium in a variety of neural cell types and implications in brain function are also discussed, including the control of gene expression, cell differentiation and programmed cell death.

From inside the book

What people are saying - Write a review

We haven't found any reviews in the usual places.


Ca Influx Through the Plasmalemma
Calcium Stores and Calcium Release Channels
Temporal and Spatial Organization of Calcium Signal in Nerve Cells

8 other sections not shown

Common terms and phrases

About the author (1995)

Kostyuk is with the National Academy of Sciences.

Bibliographic information