Cancer Associated Viruses

Front Cover
Erle S. Robertson
Springer Science & Business Media, Dec 19, 2011 - Medical - 866 pages
The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.
 

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Contents

Chapter 1 Peyton Rous A Centennial Tribute to the Founding Father of Cancer Virology
1
Chapter 2 Viruses and Cancer A Historical Perspective HBV and Prevention of a Cancer
25
Chapter 3 VirusMediated Cell Proliferation
45
Chapter 4 ViralEncoded Genes and Cancer
81
Chapter 5 Oncogenic Viruses and Cancer Transmission
101
Chapter 6 DNA Viruses and Cancer Taking a Broader Look
119
Chapter 7 Herpesviruses and Cancer
133
Chapter 8 Lymphocryptoviruses EBV and Its Role in Human Cancer
169
Chapter 18 Merkel Cell Polyomavirus
449
Chapter 19 Human Papillomaviruses and Cancer
463
Chapter 20 Tumorigenesis by Adenovirus Type 12 E1A
489
Chapter 21 Overview of Hepatitis Viruses and Cancer
509
Chapter 22 Hepadnaviruses and Hepatocellular Carcinoma
531
Chapter 23 Hepatitis C Virus and Hepatocellular Carcinoma
571
Chapter 24 Human and Animal Retroviruses HIV1 Infection Is a Risk Factor for Malignancy
585
Chapter 25 HTLV1 and Oncogenesis
613

Chapter 9 Nonhuman Primate Gammaherpesviruses and Their Role in Cancer
201
Chapter 10 Rhadinoviruses KSHV and Associated Malignancies
215
Chapter 11 Retroperitoneal Fibromatosis Herpesvirus and Kaposis SarcomaLike Tumors in Macaques
251
Chapter 12 Murine GammaherpesvirusAssociated Tumorigenesis
267
Chapter 13 Mareks Disease VirusInduced TCell Lymphomas
307
Chapter 14 Polyomaviruses and Cancer
337
Chapter 15 Polyomavirus SV40 Model Infectious Agent of Cancer
377
Chapter 16 BK Polyomavirus and Transformation
419
Chapter 17 Polyomavirus JC and Human Cancer Possible Role of Stem Cells in Pathogenesis
433
Chapter 26 Human TCell Leukemia Virus Type 2 HTLV2 Biology and Pathogenesis
647
Chapter 27 Mechanisms of Oncogenesis by Avian and Murine Retroviruses
677
Chapter 28 Rous Sarcoma Virus Contributions of a Chicken Virus to Tumor Biology Human Cancer Therapeutics and Retrovirology
705
Chapter 29 Mouse Mammary Tumor Virus and Cancer
739
Chapter 30 Jaagsiekte Sheep Retrovirus and Lung Cancer
755
Chapter 31 Small RNAs and Their Role in HerpesvirusMediated Cancers
793
Chapter 32 Viral Malignancies in HIVAssociated Immune Deficiency
819
Index
853
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