Cancer Chemoprevention

Front Cover
CRC Press, Aug 20, 1992 - Medical - 656 pages
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The ultimate goal of cancer chemoprevention research and development is the identification of pharmaceutical or dietary constituents that will prevent cancer. Cancer Chemoprevention presents the proceedings of a large workshop on cancer chemoprevention that highlights the latest knowledge in the field, in addition to issues and ideas concerning future directions. Retinoids, sulfur compounds, and a large number of many naturally occurring cancer inhibitors in the diet are discussed, including green tea, garlic constituents, citrus fruit oils, and beans and seeds containing protease inhibitors. Compounds that may prevent the formation of carcinogens in food are covered, and the mechanisms by which chemical or dietary agencts produce cancer inhibitors are discussed.
 

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Contents

Environmental Carcinogens and Anticarcinogens
3
Chemoprevention of Cancer by Naturally Occurring and Synthetic
19
Recent Results in Preclinical and Clinical Drug Development
41
Histopathology of Human Intraepithelial Neoplasia With Implications
57
Evaluation of the Results of Clinical Trials With Retinoids in Relation
71
Retinoid Chemoprevention of Lung Cancer
83
Chemoprevention of Cancer With the Synthetic Retinoid Fenretinide
95
Treatment of Field Cancerization
113
Structure Biosynthesis Evolution and Physiological and Ecological
353
Inhibitory Effect of Oral Administration of Green Tea on Tumorigenesis
361
Inhibitory Effects of Curcumin on Tumor Promotion and Arachidonic
375
Sarcophytol A and Epigallocatechin Gallate EGCG Nontoxic
393
Chemoprevention of Esophageal Cancer by Ellagic Acid and Phenethyl
407
Oncogenes and Chemoprevention
571
DEVELOPMENT
585
Drug Development Status of Four Leading Chemopreventive Agents
597

Chemoprevention by Conjugated Dienoic Isomers of Linoleic Acid
279
Antineoplastic Action of Inositol Compounds
285
Ascorbate and Tocopherol
327

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