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Pharmacology of Cancer Chemotherapy
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5-fluorouracil 6-mercaptopurine acute leukemia administration alkylating agents Assn Cancer Res bone marrow Breast Cancer breast carcinoma busulfan Cancer Chemother Rep Cancer Chemotherapy chemotherapeutic agents Chemotherapy childhood acute leukemia chlorambucil choriocarcinoma Clin clinical complete remission corticosteroids course cyclophosphamide cytarabine cytotoxic dactinomycin decrease DHFR dose drug duration effective enzyme estrogens excretion gastrointestinal given granulocytic leukemia Hodgkin's disease infusion inhibition initial injection intravenous JAMA kemia leukopenia liver lung lymphoma lymphosarcoma maintenance therapy malignant mechlorethamine median melphalan metastases methotrexate mg/kg mg/kg/day months multiple myeloma Nitrogen Mustard normal noted objective response Obstet Gynec occurred oral ovarian carcinoma partial remissions patients platelet platelet count polycythemia prednisone Proc Am Assn produced purine radiotherapy received remission rate renal reported response rate reticulum cell sarcoma serum studies survival synthesis tients tion tissue toxicity treated treatment Triethylene TSPA tumor tumor cells uric acid uric acid nephropathy vinblastine vincristine weeks white blood count Wilms