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Mechanism of Action of Chemotherapeutic Drugs
Mechanisms of Action of Purine and Pyrimidine Analogues GEORGE
Mechanism of Action of the Vinca Alkaloids JOHN H MARSDEN M D
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5-fluorouracil 6-mercaptopurine acid actinomycin activity acute leukemia adjuvant administration alkylating agents Amer androgens anemia antibiotic antibody antigens antitumor Ara-C Biol blood bone marrow busulfan Cancer Chemother cancer chemotherapy Cancer Res cellular cent chemo chemotherapeutic agents chlorambucil chronic lymphocytic leukemia Clin clinical combination cyclophosphamide diagnosis dosage dose drug effects erythropoiesis evaluation granulocytic Gynec hematologic Hodgkin's disease human immune immunologic immunotherapy increased infection inhibition interferon intravenous irradiation L-asparaginase lesions leukemic cells leukocytes lymphocytic leukemia lymphoma malignant megakaryocytes melphalan metabolism metastatic methotrexate mg/kg mice mithramycin mouse multiple myeloma myelocytic neoplasms neutrophil nitrogen mustard normal Obstet occur plasma cell platelet platelet count poly pregnancy Proc protein radiation therapy reaction reported response sarcoma sensitive serum spleen Stage stem cell studies surgery survival synthesis Table testosterone therapeutic thrombocytopenia thyroid tion tissue topical 5-FU toxicity transfusion transplantation treatment tumor cells vinblastine vincristine vitro