Cancer Chemotherapy and Biotherapy: Principles and Practice

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Bruce Chabner, Dan Louis Longo
Lippincott-Raven Publishers, 1996 - Biological products - 824 pages
This text presents a detailed description of the properties and clinical use of anticancer drugs. It provides information on all aspects of drug mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Emphasis is placed on the rationale for the use of drugs in specific schedules and combinations, and guidelines are provided by dose adjustment in particular situations. This edition includes chapters on the following: endocinre therapies; antifolates; fluropyrimidines; cytidines and purine analogues; hydroxyurea; mitotic inhibitors; alkylating agents; antitumour antibiotics; anthracyclines; topoisomerase inhibitors; enzyme therapy; and anti-AIDS drugs.

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About the author (1996)

Bruce Chabner, MD, Professor, Department of Medicine, Harvard Medical School; Clinical Director, MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts

Dan L. Longo, MD , Scientific Director, National Institute on Aging, National Institutes of Health, Bethesda, Maryland

Dan L. Longo, MD Scientific Director National Institute on Aging National Institutes of Health Bethesda, Maryland

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