Cancer Vaccines and Tumor Immunity

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John Wiley & Sons, Oct 26, 2007 - Medical - 432 pages
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Cancer Vaccines and Tumor Immunity offers a review of the basic scientific discoveries that have moved forward into clinical trials. Presented in the context of real-world human research and experimentation, these major scientific advances demonstrate how our understanding of immune activation, T-regulatory cells, and autoimmunity will impact cancer vaccine design. The authors also explain how vaccination in the context of bone marrow transplantation will open new avenues for clinical study in the future.
 

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Contents

I INTRODUCTION
1
II ADJUVANT THERAPY ENHANCING THE ENDOGENOUS IMMUNE RESPONSE
13
III ANTIGENSPECIFIC THERAPY NOVEL PRESENTATION OF PEPTIDE AND PROTEIN ANTIGENS
67
IV CELLBASED THERAPY USING CANCER CELLS AS A MEANS TO INDUCE SPECIFIC TUMOR IMMUNITY
151
V DEFINING EFFECTIVE CLINICAL RESPONSES
269
Index
309
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About the author (2007)

Rimas J. Orentas, PhD, is Associate Professor in the Department of Pediatrics, Section of Hematology-Oncology, and holds joint appointments in the Departments of Medicine and Microbiology and Molecular Genetics at the Medical College of Wisconsin in Milwaukee, Wisconsin.

James W. Hodge, PhD, is a Senior Scientist in the Laboratory of Tumor Immunology and Biology at the National Cancer Institute in Bethesda, Maryland.

Bryon D. Johnson, PhD, is Associate Professor in the Department ofPediatrics, Section of Hematology-Oncology at the Medical College of Wisconsin in Milwaukee, Wisconsin.

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