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Advances in Cancer Chemotherapy
Experimental Basis of Cancer Chemotherapy
New Leads Towards Antitumor Selectivity in Therapeutics
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5-fluorouracil acid action administration adriamycin alkylating agents animals antibiotics anticancer drugs antimetabolites antitumour activity assay BCNU Biochem bleomycin bone marrow breast cancer cancer chemotherapy Cancer Res Cancer Research carcinogenic carcinoma CCNU chemical chemother chemotherapeutic chemotherapy chlorambucil chlorozotocin chromosome clinical combination chemotherapy compounds concentrations culture cyclic AMP cyclophosphamide cytostatic cytotoxic Denekamp dianhydrogalactitol disease dosage dose effect enhancement ratios enzyme experimental Flagyl glioma Goldin growth Hellmann hypoxic cells ICRF ifosfamide increase inhibition inhibitors injection irradiation lethal leukemia levels liposomes liver malignant Maytansine metabolism metabolites metastases methotrexate mg/kg mice mouse mustard mutagenic nitrosoureas normal observed oestrogen patients pharmacokinetics pharmacological plasma Proc protein radiation radiosensitization radiotherapy reduced regression remission resistant response rate sarcoma screening sensitive streptozotocin studies survival synthesis Table therapeutic therapy thymidine tissue toxicity treatment trofosfamide tumour tumour cells UKALL Vincristine vitro vivo X-rays