Cardiac Valve Allografts 1962–1987: Current Concepts on the Use of Aortic and Pulmonary Allografts for Heart Valve Subsitutes
A.C. Yankah, R. Hetzer, C. Miller, D.N. Ross, J. Somerville, M.H. Yacoub
Steinkopff, Jan 1, 1988 - Medical - 390 pages
It was the genius of Gordon Murray in Toronto that introduced the use of allografts into cardiac surgery in the 1950s. Soon after this on opposite sides ofthe world, Sir Brian Barratt-Boyes in Auckland, New Zealand, and Mr. Donald Ross in London, undertook to use allografts for the replacement of diseased aortic valves. Since that time the global interest in allografts has been patchy, episodic, and without a con sensus. Nonetheless, for the last 20 years at least three groups in the world have steadfastly pursued the development of new and relevant information concerning the use of allograft valves in humans. These are the centres of Sir Brian Barratt Boyes, Mr. Donald Ross, and Mark O'Brien in Brisbane. More recently, talented investigators, including Drs. Yankah, Yacoub, and others, have been developing information concerning the immunological aspects of the use of allografts, as well as their clinical use. No doubt, at present, cardiac valve allografts of one sort or another are the devices of choice for conduits and have an important place in the surgery of aortic valve replacement. Even so, in the mind of this writer at least, the future usefulness of allografts for the replacement of diseased cardiac valves and conduits between a ventricle and the pulmonary artery, remains problematic, and depends upon improvements in other devices for this purpose and upon improve ments that may be made in preparing and using allografts.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Procurement and preservation techniques
Cryobiology of tissues
Endothelial and fibroblast viability assays for tissue allografts
7 other sections not shown
Other editions - View all
Actuarial allograft aortic valve allograft valve anastomosis annulus antibiotic antibiotic solution antigens aorta aortic allograft aortic homograft aortic position aortic root replacement aortic valve allograft aortic valve homografts aortic valve replacement autograft Barratt-Boyes BG Bodnar calcification cardiac cellular clinical collagen CryoLife cryopreserved cryopreserved allograft cryoprotectant cusp death degeneration diameter distal donor endocarditis endothelial cells explanted fibroblasts follow-up fresh function Gonzalez-Lavin graft heart valve histological homograft valve Hospital immunological implantation insertion Kirklin long-term method mitral valve months non-viable obstruction operation patients porcine postoperative preservation procedure PSKA pulmonary allograft pulmonary artery pulmonary atresia pulmonary valve recipient regurgitation reoperation repair right ventricle right ventricular outflow Ross DN significant Somerville stenosis sterile sterilisation storage surgery surgical survival suture line Table technique tetralogy of Fallot Thorac Cardiovasc Surg tissue tricuspid tricuspid atresia truncus arteriosus valve failure valve incompetence valved conduits ventricular outflow tract viability xenograft Yacoub Yankah