Cardiovascular Aspects of Marfan Syndrome
Roland Hetzer, Petra Gehle, Jürgen Ennker
Steinkopff, Jan 1, 1995 - Medical - 131 pages
Marfan Syndrome is a hereditary disorder of connective tissue which primarily affects the eyes, skeleton, blood vessels, and various structures of the heart.
Since 1943, when the cardiovascular manifestations of Marfan Syndrome were first described, understanding of its nature, diagnostic tools, and surgical treatment have been remarkably improved. Although the specific surgical procedures have reached an advanced standard and general acceptance, many questions remain unanswered and have given rise to ongoing controversy.
Cardiovascular Aspects of Marfan Syndrome presents the advances in understanding the cause and pathogenesis of Marfan Syndrome and its current specific surgical therapy.
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Genetic basis of Marfan syndrome
Cardiovascular pathology in Marfan syndrome An overview
Surgical therapy for Marfan syndrome Then and
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abnormalities acute dissection anastomosis annulo-aortic ectasia annulus aortic aneurysm aortic arch aortic dilatation aortic dissection aortic graft aortic operations aortic regurgitation aortic replacement aortic root replacement aortic sinuses aortic valve replacement arachnodactyly arch replacement ascending aorta Bentall Cabrol cardiac cardiovascular manifestations cause chromosome 15 chronic type clinical collagen composite graft composite valve graft connective tissue coronary arteries Coselli cusps cystic medial degeneration Dacron Dacron graft death diagnosis Dietz disease distal echocardiography ectopia lentis elastin endocarditis extracellular matrix false aneurysm fibrillin gene fibrillin polypeptide follow-up genetic heritable disorders HETZER homograft Marfan patients Marfan syn Marfan syndrome McKusick microfibrils mitral valve mitral valve prolapse molecular mortality motif mutation myocardial occur P-blockade patients undergoing patients with Marfan Peltonen phenotype pregnancy procedure prolapse prosthetic proximal Pyeritz reimplantation reoperations rupture Sakai LY Sir YACOUB skeletal surgery surgical suture Table technique Thorac Cardiovasc Surg thoracoabdominal aortic underwent valve graft replacement